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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4affects expressionISOIL4 (Homo sapiens)6480464CTDArsenic Trioxide affects the expression of IL4 proteinPMID:18357729
Il4decreases expressionISOIl4 (Mus musculus)6480464CTDArsenic Trioxide results in decreased expression of IL4 mRNAPMID:12243866 PMID:15073043
Il4decreases expressionISOIL4 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of IL4 proteinPMID:29950232
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