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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1aaffects expressionEXP 6480464CTDArsenic Trioxide affects the expression of IL1A mRNAPMID:31734849
Il1aincreases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of IL1A proteinPMID:33173984
Il1amultiple interactionsEXP 6480464CTDtrans-sodium crocetinate inhibits the reaction [Arsenic Trioxide results in increased expression of IL1A protein]PMID:33173984
Il1adecreases expressionISOIL1A (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of IL1A mRNAPMID:17530438
Il1aincreases expressionISOIL1A (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of IL1A mRNAPMID:22521957 PMID:31734849
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