GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Csf2 | decreases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased expression of CSF2 mRNA; Arsenic Trioxide results in decreased expression of CSF2 protein | PMID:29049341 | Csf2 | increases expression | ISO | Csf2 (Rattus norvegicus) | 6480464 | CTD | Arsenic Trioxide results in increased expression of CSF2 mRNA | PMID:22465848 | Csf2 | multiple interactions | ISO | CSF2 (Homo sapiens) | 6480464 | CTD | [Arsenic Trioxide co-treated with CSF2] results in decreased activity of RELA protein; [CSF2 protein co-treated with Arsenic Trioxide] affects the activity of CASP3 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and affects the activity of CASP8 protein; [CSF2 protein co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein | PMID:16174796 | | ||||||||||||||||||||||
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