GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CDK2 | decreases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased expression of CDK2 mRNA | PMID:20458559 | CDK2 | multiple interactions | EXP | | 6480464 | CTD | [ruxolitinib co-treated with Arsenic Trioxide] results in decreased expression of CDK2 mRNA; Arsenic Trioxide inhibits the reaction [PDGFB protein results in increased expression of CDK2 protein]; Arsenic Trioxide promotes the reaction [CDK2 protein binds to CDKN1A protein]; Arsenic Trioxide results in decreased expression of and results in decreased activity of CDK2 protein | PMID:12480548 PMID:30012499 PMID:35276128 | |
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