GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Chuk | decreases expression | ISO | CHUK (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of CHUK protein | PMID:22384180 | Chuk | multiple interactions | ISO | CHUK (Homo sapiens) | 6480464 | CTD | [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein; Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased phosphorylation of CHUK protein]; Arsenic Trioxide results in increased phosphorylation of and results in increased activity of CHUK protein | PMID:23949314 PMID:31307525 | | ||||||||||||||||||||||
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