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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319531
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC7A11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:30614
Term: benzo[a]pyrene diol epoxide I
Definition: An epoxide that has formula C20H14O3.
Chemical ID: MESH:D015123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC7A11affects expressionEXP 6480464CTD7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC7A11 proteinPMID:36450496
SLC7A11decreases expressionEXP 6480464CTD7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC7A11 mRNAPMID:19150397 PMID:20018196
SLC7A11multiple interactionsEXP 6480464CTDDeferoxamine affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC7A11 protein]; ferrostatin-1 affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC7A11 protein]PMID:36450496
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