GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dnmt3a | multiple interactions | ISO | DNMT3A (Homo sapiens) | 6480464 | CTD | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide promotes the reaction [DNMT3A protein binds to RARB promoter]; DNMT3A protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of JUN protein]; DNMT3A protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MAPK1 protein modified form]; DNMT3A protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MAPK3 protein modified form]; DNMT3A protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 protein modified form] | PMID:20426865 | | ||||||||||||||||||||||
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