GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL1A | increases expression | EXP | | 6480464 | CTD | Silicon Dioxide analog results in increased expression of IL1A mRNA; Silicon Dioxide results in increased expression of IL1A mRNA | PMID:19428942 PMID:22300531 PMID:23806026 PMID:25351596 PMID:32316988 | IL1A | increases secretion | EXP | | 6480464 | CTD | Silicon Dioxide results in increased secretion of IL1A protein | PMID:32316988 | IL1A | multiple interactions | EXP | | 6480464 | CTD | CXCL16 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL1A protein]; IL1RN protein affects the reaction [Silicon Dioxide results in increased secretion of IL1A protein]; IL1RN protein inhibits the reaction [Silicon Dioxide results in increased expression of IL1A mRNA]; OLR1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL1A protein]; SCARB1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL1A protein]; Silicon Dioxide results in increased expression of and results in increased secretion of IL1A protein | PMID:32316988 PMID:34653535 | IL1A | increases secretion | ISO | Il1a (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased secretion of IL1A protein | PMID:29484482 | IL1A | multiple interactions | ISO | Il1a (Mus musculus) | 6480464 | CTD | [Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein; lipopolysaccharide, E coli O55-B5 promotes the reaction [[Chromium Alloys co-treated with titanium alloy (TiAl6V4) co-treated with titanium nitride co-treated with Silicon Dioxide] results in increased expression of IL1A protein] | PMID:12168658 PMID:22155353 | | ||||||||||||||||||||||
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