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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735336
Species: Mus musculus
RGD Object: Gene
Symbol: Akt1
Name: thymoma viral proto-oncogene 1
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases methylationISOAKT1 (Homo sapiens)6480464CTDSilicon Dioxide results in decreased methylation of AKT1 promoterPMID:34973136
Akt1decreases phosphorylationISOAkt1 (Rattus norvegicus)6480464CTDSilicon Dioxide analog results in decreased phosphorylation of AKT1 proteinPMID:27613482
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