GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | JAK2 | decreases expression | EXP | | 6480464 | CTD | Silicon Dioxide results in decreased expression of JAK2 mRNA | PMID:25351596 | JAK2 | increases phosphorylation | EXP | | 6480464 | CTD | Silicon Dioxide results in increased phosphorylation of JAK2 protein | PMID:29894800 | JAK2 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein] | PMID:29894800 | |
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