GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il18 | increases secretion | EXP | | 6480464 | CTD | Silicon Dioxide analog results in increased secretion of IL18 protein | PMID:27311643 | Il18 | multiple interactions | EXP | | 6480464 | CTD | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein]; diphenyleneiodonium inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein] | PMID:27311643 | Il18 | increases expression | ISO | Il18 (Rattus norvegicus) | 6480464 | CTD | Silicon Dioxide results in increased expression of IL18 mRNA | PMID:32721576 | Il18 | increases expression | ISO | IL18 (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased expression of IL18 mRNA; Silicon Dioxide results in increased expression of IL18 protein | PMID:23806026 PMID:34766707 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |