GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il12b | affects response to substance | ISO | Il12b (Mus musculus) | 6480464 | CTD | IL12B protein affects the susceptibility to Silicon Dioxide | PMID:12193738 | Il12b | decreases response to substance | ISO | Il12b (Mus musculus) | 6480464 | CTD | IL12B gene mutant form results in decreased susceptibility to Silicon Dioxide | PMID:12193738 | Il12b | increases expression | ISO | Il12b (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased expression of IL12B mRNA | PMID:29341224 | Il12b | multiple interactions | ISO | Il12b (Mus musculus) | 6480464 | CTD | IL12A gene mutant form promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein]; Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein | PMID:12193738 | | ||||||||||||||||||||||
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