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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620761
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Notch3
Name: notch receptor 3
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Notch3decreases expressionISONOTCH3 (Homo sapiens)6480464CTDSilicon Dioxide analog results in decreased expression of NOTCH3 mRNAPMID:23806026
Notch3decreases methylationISONOTCH3 (Homo sapiens)6480464CTDSilicon Dioxide results in decreased methylation of NOTCH3 genePMID:34973136
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