GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod3 | decreases expression | ISO | Sod3 (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in decreased expression of SOD3 mRNA; Silicon Dioxide results in decreased expression of SOD3 protein | PMID:30453980 | Sod3 | increases response to substance | ISO | Sod3 (Mus musculus) | 6480464 | CTD | SOD3 gene mutant form results in increased susceptibility to Silicon Dioxide | PMID:30453980 | Sod3 | multiple interactions | ISO | Sod3 (Mus musculus) | 6480464 | CTD | [SOD3 gene mutant form results in increased susceptibility to Silicon Dioxide] which results in increased expression of CCL2 mRNA; [SOD3 gene mutant form results in increased susceptibility to Silicon Dioxide] which results in increased expression of S100A4 mRNA; [SOD3 gene mutant form results in increased susceptibility to Silicon Dioxide] which results in increased expression of TIMP1 mRNA | PMID:30453980 | |
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