GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gli2 | increases expression | EXP | | 6480464 | CTD | Silicon Dioxide results in increased expression of GLI2 protein | PMID:31181250 | Gli2 | multiple interactions | EXP | | 6480464 | CTD | [goralatide co-treated with Captopril] inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]; AGT protein modified form inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]; Captopril inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein]; goralatide inhibits the reaction [Silicon Dioxide results in increased expression of GLI2 protein] | PMID:31181250 | Gli2 | decreases expression | ISO | GLI2 (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in decreased expression of GLI2 mRNA | PMID:23806026 | | ||||||||||||||||||||||
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