GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfa | increases expression | ISO | TGFA (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased expression of TGFA mRNA | PMID:25895662 | Tgfa | increases secretion | ISO | TGFA (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased secretion of TGFA protein | PMID:24844442 | Tgfa | multiple interactions | ISO | TGFA (Homo sapiens) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Silicon Dioxide analog results in increased secretion of TGFA protein]; CXCL16 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of TGFA protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Silicon Dioxide analog results in increased secretion of TGFA protein]; SCARB1 mRNA promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of TGFA protein]; Silicon Dioxide results in increased expression of and results in increased secretion of TGFA protein | PMID:24844442 PMID:34653535 | | ||||||||||||||||||||||
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