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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10499
Species: Mus musculus
RGD Object: Gene
Symbol: Edn1
Name: endothelin 1
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn1decreases expressionEXP 6480464CTDSilicon Dioxide results in decreased expression of EDN1 mRNAPMID:30453980
Edn1increases expressionEXP 6480464CTDSilicon Dioxide results in increased expression of EDN1 mRNAPMID:19073995 PMID:33720480
Edn1decreases expressionISOEDN1 (Homo sapiens)6480464CTDSilicon Dioxide analog results in decreased expression of EDN1 mRNAPMID:25895662
Edn1increases expressionISOEDN1 (Homo sapiens)6480464CTDSilicon Dioxide results in increased expression of EDN1 mRNAPMID:25351596
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