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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10473
Species: Mus musculus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H dehydrogenase, quinone 1
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1affects secretionISONQO1 (Homo sapiens)6480464CTDSilicon Dioxide analog affects the secretion of NQO1 proteinPMID:25895662
Nqo1increases expressionISONQO1 (Homo sapiens)6480464CTDSilicon Dioxide results in increased expression of NQO1 mRNA; Silicon Dioxide results in increased expression of NQO1 proteinPMID:25351596 PMID:32097614
Nqo1multiple interactionsISONQO1 (Homo sapiens)6480464CTDtanshinone promotes the reaction [Silicon Dioxide results in increased expression of NQO1 protein]PMID:32097614
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