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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732221
Species: Homo sapiens
RGD Object: Gene
Symbol: GSR
Name: glutathione-disulfide reductase
Acc ID: CHEBI:30512
Term: silver atom
Definition: A copper group element atom that has formula Ag.
Chemical ID: MESH:D012834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSRincreases activityEXP 6480464CTDSilver analog results in increased activity of GSR proteinPMID:27113704
GSRmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Silver analog results in increased activity of GSR protein]PMID:27113704
GSRaffects expressionISOGsr (Mus musculus)6480464CTDSilver affects the expression of GSR mRNAPMID:19429238
GSRdecreases expressionISOGsr (Rattus norvegicus)6480464CTDSilver results in decreased expression of GSR mRNAPMID:26277626
GSRincreases activityISOGsr (Rattus norvegicus)6480464CTDSilver results in increased activity of GSR proteinPMID:26277626
GSRincreases expressionISOGsr (Mus musculus)6480464CTDSilver results in increased expression of GSR mRNAPMID:27131904
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