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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348437
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:3020
Term: benzalkonium chloride
Definition: A class of quaternary ammonium chloride salts in which the nitrogen is substituted by a benzyl group, two methyl groups and an even-numbered alkyl chain.
Chemical ID: MESH:D001548
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9increases activityISOMmp9 (Rattus norvegicus)6480464CTDBenzalkonium Compounds results in increased activity of MMP9 proteinPMID:21058936
MMP9multiple interactionsISOMmp9 (Mus musculus)6480464CTD[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNAPMID:30171875
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