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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69149
Species: Homo sapiens
RGD Object: Gene
Symbol: GHR
Name: growth hormone receptor
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GHRdecreases expressionISOGhr (Rattus norvegicus)6480464CTDZinc deficiency results in decreased expression of GHR mRNA; Zinc deficiency results in decreased expression of GHR proteinPMID:10985758 PMID:7722689
GHRmultiple interactionsISOGhr (Rattus norvegicus)6480464CTDGH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR mRNA]; GH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR protein]PMID:10985758
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