Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2affects localizationEXP 6480464CTDZinc deficiency affects the localization of NFE2L2 proteinPMID:23377617
Nfe2l2multiple interactionsEXP 6480464CTD[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased expression of NFE2L2 proteinPMID:37415728
Nfe2l2affects localizationISONFE2L2 (Homo sapiens)6480464CTDZinc deficiency affects the localization of NFE2L2 proteinPMID:23377617
Nfe2l2decreases expressionISONfe2l2 (Mus musculus)6480464CTDZinc deficiency results in decreased expression of NFE2L2 proteinPMID:21078376
Nfe2l2increases activityISONFE2L2 (Homo sapiens)6480464CTDZinc results in increased activity of NFE2L2 promoterPMID:21643505
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein affects the reaction [Zinc results in increased expression of HMOX1 mRNA]; Zinc deficiency promotes the reaction [Dietary Fats results in decreased expression of NFE2L2 protein]; Zinc inhibits the reaction [Dietary Fats results in decreased expression of and affects the localization of NFE2L2 protein]PMID:10473555 PMID:27370414
Go Back to source page   Continue to Ontology report