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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprmultiple interactionsEXP 6480464CTD[LEPR gene mutant form results in increased susceptibility to Ethanol] which results in decreased abundance of ZincPMID:15475485
Leprmultiple interactionsISOLepr (Mus musculus)6480464CTD[Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of LEPR mRNA; [Zinc deficiency co-treated with Ethanol] results in increased expression of LEPR mRNAPMID:24155903 PMID:33549593
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