GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lep | increases expression | EXP | | 6480464 | CTD | Zinc deficiency results in increased expression of LEP protein | PMID:20660286 | Lep | decreases abundance | ISO | LEP (Homo sapiens) | 6480464 | CTD | LEP gene mutant form results in decreased abundance of Zinc | PMID:10965932 | Lep | decreases expression | ISO | LEP (Homo sapiens) | 6480464 | CTD | Zinc results in decreased expression of LEP mRNA | PMID:18316168 | Lep | decreases expression | ISO | Lep (Mus musculus) | 6480464 | CTD | Zinc deficiency results in decreased expression of LEP protein | PMID:25088245 | Lep | multiple interactions | ISO | LEP (Homo sapiens) | 6480464 | CTD | IL6 promoter polymorphism affects the reaction [Zinc results in decreased expression of LEP mRNA]; MT1A gene polymorphism affects the reaction [Zinc results in decreased expression of LEP mRNA] | PMID:18316168 | Lep | multiple interactions | ISO | Lep (Mus musculus) | 6480464 | CTD | [Zinc deficiency co-treated with Ethanol] results in decreased expression of and results in decreased secretion of LEP protein | PMID:24155903 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |