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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1615155
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfaip3
Name: tumor necrosis factor, alpha-induced protein 3
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfaip3increases expressionISOTNFAIP3 (Homo sapiens)6480464CTDZinc results in increased expression of TNFAIP3 mRNA; Zinc results in increased expression of TNFAIP3 proteinPMID:20427734 PMID:21035309
Tnfaip3multiple interactionsISOTNFAIP3 (Homo sapiens)6480464CTDZinc deficiency inhibits the reaction [Lipopolysaccharides results in increased activity of TNFAIP3 protein]; Zinc deficiency inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 mRNA]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TNFAIP3 protein]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]]PMID:15451058 PMID:21035309
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