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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346147
Species: Homo sapiens
RGD Object: Gene
Symbol: ALPL
Name: alkaline phosphatase, biomineralization associated
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALPLdecreases expressionISOAlpl (Rattus norvegicus)6480464CTDZinc deficiency results in decreased expression of ALPL mRNAPMID:21893222
ALPLincreases expressionISOAlpl (Rattus norvegicus)6480464CTDZinc results in increased expression of ALPL mRNAPMID:16413754
ALPLmultiple interactionsISOAlpl (Mus musculus)6480464CTD[Zinc binds to calcium silicate] which results in increased expression of ALPL mRNAPMID:23483914
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