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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2457
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Acc ID: CHEBI:3015
Term: benomyl
Definition: A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops.
Chemical ID: MESH:D001542
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp19a1increases activityISOCYP19A1 (Homo sapiens)6480464CTDBenomyl results in increased activity of CYP19A1 proteinPMID:14691014
Cyp19a1increases expressionISOCYP19A1 (Homo sapiens)6480464CTDBenomyl results in increased expression of CYP19A1 mRNAPMID:14691014 PMID:25543211
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