GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Map3k8 | increases degradation | ISO | Map3k8 (Mus musculus) | 6480464 | CTD | Lithium results in increased degradation of MAP3K8 protein alternative form | PMID:19159680 | Map3k8 | multiple interactions | ISO | Map3k8 (Mus musculus) | 6480464 | CTD | [Lithium results in increased degradation of NFKB1 protein] inhibits the reaction [NFKB1 protein binds to MAP3K8 protein]; [Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein] which results in increased phosphorylation of MAP2K1 protein; Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP3K8 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein | PMID:19159680 | | ||||||||||||||||||||||
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