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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736747
Species: Homo sapiens
RGD Object: Gene
Symbol: ALDH1A1
Name: aldehyde dehydrogenase 1 family member A1
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALDH1A1affects bindingEXP 6480464CTDALDH1A1 protein binds to CopperPMID:15359738
ALDH1A1increases expressionISOAldh1a1 (Rattus norvegicus)6480464CTDCopper results in increased expression of ALDH1A1 mRNAPMID:30556269
ALDH1A1multiple interactionsISOAldh1a1 (Mus musculus)6480464CTD[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of ALDH1A1 mRNAPMID:15467011
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