GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | FN1 | affects binding | EXP | | 6480464 | CTD | FN1 protein binds to Copper | PMID:23896426 | FN1 | multiple interactions | EXP | | 6480464 | CTD | [FN1 protein co-treated with [Clioquinol binds to Copper]] results in increased expression of EGFR protein; [NSC 689534 binds to Copper] which results in increased expression of FN1 mRNA; FN1 protein promotes the reaction [[Clioquinol binds to Copper] which results in increased phosphorylation of EGFR protein] | PMID:18346929 PMID:20971185 | FN1 | increases expression | ISO | Fn1 (Rattus norvegicus) | 6480464 | CTD | Copper deficiency results in increased expression of FN1 mRNA | PMID:17418555 | |
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