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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1multiple interactionsEXP 6480464CTD[Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 mRNA; [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 proteinPMID:31491480
Sqstm1multiple interactionsISOSQSTM1 (Homo sapiens)6480464CTD[Chelating Agents binds to Copper] which results in increased expression of SQSTM1 mRNA; [Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein; [NSC 689534 binds to Copper] which results in increased expression of SQSTM1 mRNA; [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNAPMID:20971185 PMID:25167922 PMID:25301941 PMID:30911355
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