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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736398
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1B
Name: heat shock protein family A (Hsp70) member 1B
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Bmultiple interactionsEXP 6480464CTD[Chelating Agents binds to Copper] which results in increased expression of HSPA1B mRNA; [Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA; [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1B mRNAPMID:24690739 PMID:25167922 PMID:30911355
HSPA1Bincreases expressionISOHspa1b (Rattus norvegicus)6480464CTDCopper results in increased expression of HSPA1B mRNAPMID:22465980
HSPA1Bincreases expressionISOHspa1b (Mus musculus)6480464CTDCopper results in increased expression of HSPA1B mRNAPMID:16629173
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