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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732802
Species: Mus musculus
RGD Object: Gene
Symbol: Ide
Name: insulin degrading enzyme
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDCopper affects the reaction [IDE protein affects the degradation of IAPP protein]

PMID:24719342
affects activityISORGD:28616480464CTDCopper affects the activity of IDE protein

PMID:22819648
decreases activityISORGD:28616480464CTDCopper results in decreased activity of IDE protein

PMID:24719342
multiple interactionsISORGD:7328016480464CTDCopper affects the reaction [IDE protein affects the degradation of IAPP protein]

PMID:24719342
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.