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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730924
Species: Mus musculus
RGD Object: Gene
Symbol: E2f1
Name: E2F transcription factor 1
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
E2f1increases expressionISOE2f1 (Rattus norvegicus)6480464CTDCopper deficiency results in increased expression of E2F1 mRNAPMID:17418555
E2f1multiple interactionsISOE2F1 (Homo sapiens)6480464CTD[Chelating Agents binds to Copper] which results in decreased expression of E2F1 mRNA; [Chelating Agents binds to Copper] which results in increased expression of E2F1 mRNA; [NSC 689534 binds to Copper] which results in decreased expression of E2F1 mRNAPMID:20971185 PMID:30911355 PMID:31162603
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