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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Glrx
Name: glutaredoxin
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glrxincreases expressionEXP 6480464CTDCopper results in increased expression of GLRX mRNAPMID:22465980
Glrxaffects bindingISOGLRX (Homo sapiens)6480464CTDCopper binds to GLRX proteinPMID:24522867
Glrxmultiple interactionsISOGLRX (Homo sapiens)6480464CTD[NSC 689534 binds to Copper] which results in increased expression of GLRX mRNA; GLRX protein results in decreased uptake of and results in decreased abundance of and results in decreased susceptibility to CopperPMID:20971185 PMID:24816595
Glrxmultiple interactionsISOGlrx (Mus musculus)6480464CTDGLRX protein results in decreased uptake of and results in decreased abundance of and results in decreased susceptibility to CopperPMID:24816595
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