GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | increases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | Copper results in increased expression of CCND1 mRNA; Copper results in increased expression of CCND1 protein | PMID:18245776 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | [Chelating Agents binds to Copper] which results in decreased expression of CCND1 mRNA; [Thiosemicarbazones binds to Copper] which results in decreased expression of CCND1 protein | PMID:20931265 PMID:30911355 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of CCND1 mRNA; ATOX1 protein promotes the reaction [Copper results in increased expression of CCND1 protein]; Copper promotes the reaction [ATOX1 protein binds to CCND1 promoter] | PMID:15467011 PMID:18245776 | | ||||||||||||||||||||||
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