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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621872
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt-co2
Name: mitochondrially encoded cytochrome c oxidase II
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt-co2affects activityISOmt-Co2 (Mus musculus)6480464CTDCopper deficiency affects the activity of COX2 proteinPMID:19845829
Mt-co2decreases expressionISOMT-CO2 (Homo sapiens)6480464CTDCopper deficiency results in decreased expression of COX2 proteinPMID:24708542
Mt-co2multiple interactionsISOMT-CO2 (Homo sapiens)6480464CTD[AP1S1 gene mutant form affects the metabolism of Copper] which results in decreased expression of COX2 proteinPMID:23423674
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