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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2710
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Glul
Name: glutamate-ammonia ligase
Acc ID: CHEBI:30052
Term: copper(0)
Definition: An elemental copper that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glulmultiple interactionsISOGLUL (Homo sapiens)6480464CTD[NSC 689534 binds to Copper] which results in decreased expression of GLUL mRNA; [Thiosemicarbazones binds to Copper] which results in increased expression of GLUL proteinPMID:20931265 PMID:20971185
Glulmultiple interactionsISOGlul (Mus musculus)6480464CTD[ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of GLUL mRNAPMID:15467011
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