GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | multiple interactions | EXP | | 6480464 | CTD | [Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein]; Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein] | PMID:34577062 | Akt1 | decreases phosphorylation | ISO | Akt1 (Mus musculus) | 6480464 | CTD | Copper analog results in decreased phosphorylation of AKT1 protein | PMID:22000994 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Copper results in increased phosphorylation of and results in increased activity of AKT1 protein]; [Chelating Agents binds to Copper] which results in decreased expression of AKT1 mRNA; [Chelating Agents binds to Copper] which results in decreased phosphorylation of AKT1 protein; [Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein; [Organoselenium Compounds binds to Copper] which results in decreased expression of AKT1 protein; Copper results in increased phosphorylation of and results in increased activity of AKT1 protein; Wortmannin inhibits the reaction [Copper results in increased phosphorylation of and results in increased activity of AKT1 protein] | PMID:16648635 PMID:16973122 PMID:25167922 PMID:30911355 | | ||||||||||||||||||||||
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