GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CAT | decreases activity | EXP | | 6480464 | CTD | arsenite results in decreased activity of CAT protein | PMID:31935557 | CAT | decreases expression | EXP | | 6480464 | CTD | arsenite results in decreased expression of CAT mRNA; arsenite results in decreased expression of CAT protein | PMID:18392098 PMID:22040890 | CAT | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in decreased expression of CAT protein]; 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-1,3-dihydro-2H-indol-2-one inhibits the reaction [arsenite results in decreased expression of CAT protein]; [arsenite co-treated with Curcumin] results in increased expression of CAT protein; CAT protein inhibits the reaction [arsenite results in increased expression of MIR21 mRNA]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of MAPK1 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of MAPK3 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of RELA protein] | PMID:18392098 PMID:22040890 PMID:22387281 | CAT | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | arsenite results in decreased activity of CAT protein | PMID:34339004 | CAT | decreases expression | ISO | Cat (Mus musculus) | 6480464 | CTD | arsenite results in decreased expression of CAT mRNA; arsenite results in decreased expression of CAT protein | PMID:20096321 PMID:33010264 | CAT | decreases oxidation | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | CAT protein results in decreased oxidation of arsenite | PMID:18619986 | CAT | decreases response to substance | ISO | Cat (Mus musculus) | 6480464 | CTD | CAT protein results in decreased susceptibility to arsenite | PMID:9548797 | CAT | increases expression | ISO | Cat (Mus musculus) | 6480464 | CTD | arsenite results in increased expression of CAT mRNA | PMID:18929588 | CAT | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [CAT protein results in decreased oxidation of arsenite] which results in decreased chemical synthesis of arsenic acid; Telmisartan inhibits the reaction [arsenite results in decreased activity of CAT protein] | PMID:18619986 PMID:34339004 | CAT | multiple interactions | ISO | Cat (Mus musculus) | 6480464 | CTD | CAT protein inhibits the reaction [arsenite results in increased expression of MIR21 mRNA]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of MAPK1 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of MAPK3 protein]; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of RELA protein]; Tea inhibits the reaction [arsenite results in decreased expression of CAT protein] | PMID:14516795 PMID:20096321 PMID:22387281 | |
Go Back to source page | Continue to Ontology report |