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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730981
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1B
Name: interleukin 1 beta
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1Bdecreases expressionEXP 6480464CTDarsenite results in decreased expression of IL1B mRNAPMID:23974009
IL1Bdecreases expressionISOIl1b (Mus musculus)6480464CTDarsenite results in decreased expression of IL1B mRNAPMID:18191166
IL1Bincreases expressionISOIl1b (Mus musculus)6480464CTDarsenite results in increased expression of IL1B mRNA; arsenite results in increased expression of IL1B proteinPMID:37442281
IL1Bincreases expressionISOIl1b (Rattus norvegicus)6480464CTDarsenite results in increased expression of IL1B proteinPMID:34339004
IL1Bmultiple interactionsISOIl1b (Mus musculus)6480464CTD[Arsenic Trioxide results in increased abundance of arsenite] which results in increased expression of IL1B proteinPMID:36791901
IL1Bmultiple interactionsISOIl1b (Rattus norvegicus)6480464CTDTelmisartan inhibits the reaction [arsenite results in increased expression of IL1B protein]PMID:34339004
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