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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69262
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdo1
Name: cysteine dioxygenase type 1
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdo1decreases expressionISOCdo1 (Mus musculus)6480464CTDarsenite results in decreased expression of CDO1 mRNAPMID:18191166
Cdo1increases methylationISOCDO1 (Homo sapiens)6480464CTDarsenite results in increased methylation of CDO1 promoterPMID:23974009
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