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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62287
Species: Mus musculus
RGD Object: Gene
Symbol: Pten
Name: phosphatase and tensin homolog
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptendecreases expressionISOPTEN (Homo sapiens)6480464CTDarsenite results in decreased expression of PTEN proteinPMID:22387281
Ptenmultiple interactionsISOPTEN (Homo sapiens)6480464CTDRELA mutant form inhibits the reaction [arsenite results in decreased expression of PTEN protein]PMID:22387281
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