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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605733
Species: Homo sapiens
RGD Object: Gene
Symbol: HBEGF
Name: heparin binding EGF like growth factor
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HBEGFmultiple interactionsEXP 6480464CTD[[sodium arsenite results in increased abundance of arsenite] which co-treated with HBEGF protein] results in increased expression of CCND1 mRNA; [[sodium arsenite results in increased abundance of arsenite] which co-treated with HBEGF protein] results in increased expression of CCND1 protein; [sodium arsenite results in increased abundance of arsenite] promotes the reaction [HBEGF protein results in increased phosphorylation of MAPK1 protein]; [sodium arsenite results in increased abundance of arsenite] promotes the reaction [HBEGF protein results in increased phosphorylation of MAPK3 protein]PMID:31616959
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