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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557635
Species: Mus musculus
RGD Object: Gene
Symbol: Hs6st2
Name: heparan sulfate 6-O-sulfotransferase 2
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hs6st2decreases expressionEXP 6480464CTDarsenite results in decreased expression of HS6ST2 mRNAPMID:15894712
Hs6st2multiple interactionsEXP 6480464CTD[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of HS6ST2 mRNAPMID:15894712
Hs6st2increases methylationISOHS6ST2 (Homo sapiens)6480464CTDarsenite results in increased methylation of HS6ST2 promoterPMID:23974009
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