GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | DAPK1 | increases expression | EXP | | 6480464 | CTD | arsenite results in increased expression of DAPK1 mRNA; arsenite results in increased expression of DAPK1 protein | PMID:30177839 | DAPK1 | increases methylation | EXP | | 6480464 | CTD | arsenite results in increased methylation of DAPK1 promoter | PMID:23974009 | DAPK1 | multiple interactions | EXP | | 6480464 | CTD | arsenite promotes the reaction [TP53 protein binds to DAPK1 protein]; DAPK1 protein inhibits the reaction [arsenite results in increased expression of MDM2 protein modified form]; DAPK1 protein inhibits the reaction [arsenite results in increased expression of MDM2 protein]; DAPK1 protein promotes the reaction [arsenite results in decreased expression of IKBKB mRNA]; DAPK1 protein promotes the reaction [arsenite results in decreased expression of IKBKB protein]; DAPK1 protein promotes the reaction [arsenite results in increased expression of ETS1 protein]; DAPK1 protein promotes the reaction [arsenite results in increased expression of GADD45A protein]; DAPK1 protein promotes the reaction [arsenite results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [arsenite results in increased expression of TP53 protein] | PMID:30177839 | | ||||||||||||||||||||||
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