GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tac2 | multiple interactions | EXP | | 6480464 | CTD | Benzo(a)pyrene promotes the reaction [AHR protein binds to TAC2 promoter] | PMID:19654925 | Tac2 | increases expression | ISO | Tac3 (Rattus norvegicus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of TAC2 mRNA | PMID:22374506 | Tac2 | increases methylation | ISO | TAC3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of TAC3 5' UTR; Benzo(a)pyrene results in increased methylation of TAC3 promoter | PMID:27901495 | |
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