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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735831
Species: Mus musculus
RGD Object: Gene
Symbol: Ccng1
Name: cyclin G1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccng1decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of CCNG1 mRNAPMID:22228805
Ccng1increases expressionEXP 6480464CTDBenzo(a)pyrene metabolite results in increased expression of CCNG1 mRNA; Benzo(a)pyrene results in increased expression of CCNG1 mRNAPMID:19770486 PMID:21569818 PMID:21715664 PMID:21964900 PMID:22342234 PMID:22610609 PMID:23735875 PMID:32553695 PMID:35678645
Ccng1multiple interactionsEXP 6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CCNG1 mRNAPMID:27858113
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