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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735039
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Colec12
Name: collectin sub-family member 12
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Colec12affects methylationISOCOLEC12 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of COLEC12 intron; Benzo(a)pyrene affects the methylation of COLEC12 promoterPMID:27901495 PMID:30157460
Colec12decreases expressionISOCOLEC12 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of COLEC12 mRNAPMID:20064835
Colec12decreases expressionISOColec12 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of COLEC12 mRNAPMID:19770486
Colec12increases expressionISOCOLEC12 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of COLEC12 mRNAPMID:20106945 PMID:21632981 PMID:22316170
Colec12increases expressionISOColec12 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of COLEC12 mRNAPMID:22228805
Colec12multiple interactionsISOColec12 (Mus musculus)6480464CTDAHR protein affects the reaction [Benzo(a)pyrene affects the expression of COLEC12 mRNA]PMID:22228805
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