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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734299
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2L11
Name: BCL2 like 11
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2L11affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of BCL2L11 promoterPMID:27901495
BCL2L11decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of BCL2L11 mRNAPMID:26238291
BCL2L11increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of BCL2L11 mRNAPMID:15735009
BCL2L11increases methylationEXP 6480464CTDBenzo(a)pyrene results in increased methylation of BCL2L11 3' UTR; Benzo(a)pyrene results in increased methylation of BCL2L11 5' UTRPMID:27901495
BCL2L11decreases expressionISOBcl2l11 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of BCL2L11 mRNAPMID:20713471
BCL2L11decreases methylationISOBcl2l11 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of BCL2L11 3' UTR; Benzo(a)pyrene results in decreased methylation of BCL2L11 exon; Benzo(a)pyrene results in decreased methylation of BCL2L11 intronPMID:27901495
BCL2L11increases expressionISOBcl2l11 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of BCL2L11 mRNAPMID:19770486 PMID:21715664
BCL2L11increases methylationISOBcl2l11 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased methylation of BCL2L11 genePMID:28476633
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